What Is Semax 10MG?

Type Synthetic Neuropeptide / ACTH Analog CAS Number 80714-61-0 Molecular Weight 810.9 g/mol Molecular Weight (Cu) N/A Amino Acids 7 Amino Acids Sequence Met-Glu-His-Phe-Pro-Gly-Pro

Stability Information

High-purity synthetic heptapeptideHighly stable in lyophilized formSensitive to light and high temperatures after reconstitution Lyophilized (powder) -20°C · up to 2 years Reconstituted 2-8°C · up to 30 days

About Semax 10MG

Semax is a synthetic analog of the adrenocorticotropic hormone (ACTH) fragment 4-10. It was originally developed to investigate cognitive enhancement and neuroprotection in settings of brain ischemia and hypoxia. Unlike the parent hormone, Semax is devoid of hormonal activity but possesses significant neurotrophic properties. In research settings, it is primarily studied for its ability to increase the levels of Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF). This heptapeptide serves as a vital reagent for exploring synaptic plasticity, memory formation, and the cellular mechanisms of neurorecovery following injury. Its stable, lyophilized form ensures consistency in neurochemical and behavioral assays.

Mechanism of Action

The mechanism involves Semax crossing the blood-brain barrier (in experimental models) and stimulating the synthesis of neurotrophins like BDNF and NGF. These factors are crucial for the survival, development, and function of neurons. Additionally, Semax modulates the expression of genes involved in the immune response and neurotransmitter metabolism (specifically dopamine and serotonin). It also acts as an antioxidant and anti-hypoxic agent, protecting neuronal cells from the damage caused by glutamate toxicity and oxidative stress in research assays.

What Research Has Shown

Neuroscience Research 99 Purity Percentage (HPLC Verified) BDNF Expression & Neuroprotection Semax Treated Group 88.5% Control Group 18.0% Trial details: Investigative studies focusing on the upregulation of Brain-Derived Neurotrophic Factor (BDNF) and the protection of neurons against oxidative stress in experimental stroke models. Cognitive Results

Neurogenesis & Memory Optimization

Findings from neurotrophic factor investigations

92% BDNF Signaling Enhanced Synaptic Plasticity 85% Neuroprotection Reduced Hypoxic Damage Note: Results highlight the compound’s potential as a potent tool for cognitive enhancement and recovery research.

Research Highlights

Neurotrophic Factor Stimulation

Research focusing on the upregulation of BDNF and NGF for neuronal survival and growth.

Cognitive & Memory Enhancement

Investigating the stabilization of synaptic connections and its impact on learning capacity.

Neuroprotective Pathways

Studies exploring the peptide’s role in protecting brain tissue during ischemic or hypoxic events.

Gene Expression Regulation

Exploration of how Semax resets gene patterns related to neuroinflammation and cellular repair.

Product Specifications

Molecular Formula
C₆₂H₉₈N₁₆O₂₂
Molecular Weight
1419.53 g/mol
Sequence
Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Purity
≥99% (HPLC verified)
Form
Lyophilized powder
Appearance
White to off-white powder
Solubility
Soluble in water, bacteriostatic water
Storage
-20°C (lyophilized), 2-8°C (reconstituted)

Research Studies

Semax: A Neuropeptide Analog for Neuroprotection and Recovery

A comprehensive analysis of the peptide’s impact on BDNF levels and cognitive markers in animal models.

Gusev E.I. & Skvortsova V.I. (2024) View Full Study

Frequently Asked Questions

What is the origin of Semax?

Semax is a synthetic analog of a fragment of the Adrenocorticotropic Hormone (ACTH 4-10), specifically modified for cognitive and neuroprotective research.

Does Semax have hormonal side effects?

No, because of its specific structure, it lacks the hormonal activity usually associated with ACTH, focusing entirely on neurotrophic and neuroprotective pathways.

Frequently bought together: BPC & TB Blend, BPC-157, KLOW Blend