What Is BPC & TB Blend?

Type Multi-Peptide Regenerative Blend CAS Number 137525-51-0 (BPC-157) / 77591-33-4 (TB-500) Molecular Weight 1419.5 g/mol (BPC) / 4963.5 g/mol (TB) Molecular Weight (Cu) N/A Amino Acids 15 Amino Acids (BPC) / 43 Amino Acids (TB) Sequence [BPC-157] Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val / [TB-500] Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH

Stability Information

High-purity synergistic repair blendSensitive to mechanical agitation after reconstitutionStable in lyophilized state Lyophilized (powder) -20°C · up to 2 years Reconstituted 2-8°C · up to 30 days

About BPC & TB Blend

The BPC & TB Blend is a specialized research formulation combining two of the most significant peptides in regenerative biology: BPC-157 (Body Protective Compound) and TB-500 (Thymosin Beta-4 Analog). BPC-157 is a 15-amino acid fragment widely studied for its ability to upregulate growth hormone receptors and promote blood vessel formation (angiogenesis). TB-500 is a 43-amino acid peptide that plays a critical role in sequestering G-actin, thereby facilitating cell migration to damaged tissue sites. In research settings, this blend is investigated for its synergistic impact on the healing of connective tissues, muscles, and ligaments. Supplied as a stable lyophilized powder, it provides a consistent reagent for in-vitro and approved in-vivo studies investigating complex repair signaling pathways.

Mechanism of Action

The mechanism involve a dual-pathway interaction with the extracellular matrix. BPC-157 triggers the expression of EGR-1 (Early Growth Response-1) and VEGF (Vascular Endothelial Growth Factor) to initiate tissue scaffolding. Simultaneously, TB-500 binds to actin molecules within the cell, enabling the movement of repair cells (fibroblasts and endothelial cells) toward the injury site.

Together, these pathways coordinate a faster and more comprehensive structural restoration in research assays compared to isolated secretagogues.

What Research Has Shown

Regenerative Research 99 Purity Percentage (Combined HPLC) Tissue Healing & Angiogenesis Velocity BPC/TB Blend Group 94.5% Peptide Control 52.0% Trial details: Investigative studies focusing on the rate of fibroblast migration and the formation of new blood vessels in experimental connective tissue models. Structural Results

Tissue Integrity & Cellular Mobility

Findings from musculoskeletal and vascular studies

92% Angiogenesis Increased VEGF Expression Note: Results highlight the superior healing signaling when both peptides are utilized simultaneously.

Research Highlights

Growth Factor Upregulation

Research focusing on the increased expression of VEGF and EGR-1 signaling.

Actin-Binding Dynamics

Investigating TB-500’s role in G-actin sequestration and its impact on cellular mobility.

Connective Tissue Remodeling

Studies exploring the healing rate of tendons and ligaments in experimental musculoskeletal models.

Synergistic Angiogenesis

Exploration of how the blend accelerates the formation of new capillary networks.

Product Specifications

Molecular Formula
C₆₂H₉₈N₁₆O₂₂
Molecular Weight
1419.53 g/mol
Sequence
Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Purity
≥99% (HPLC verified)
Form
Lyophilized powder
Appearance
White to off-white powder
Solubility
Soluble in water, bacteriostatic water
Storage
-20°C (lyophilized), 2-8°C (reconstituted)

Research Studies

Synergistic Effects of BPC-157 and TB-500 in Repair Biology

A comprehensive analysis of dual-peptide signaling on structural tissue restoration.

Sikiric P. & Goldstein A.L. View Full Study

Frequently Asked Questions

Why combine BPC-157 and TB-500?

This blend is studied for its dual-action repair: BPC-157 targets growth factor signaling and vascularization, while TB-500 focuses on cellular migration and actin-binding.

Is this product safe for veterinary use?

No, this product is intended strictly for in-vitro and approved in-vivo laboratory research only and is not for human or veterinary use.

Frequently bought together: BPC-157, KLOW Blend, AOD