What Is DSIP?
Type Sleep Modulator CAS Number 62568-57-4 Molecular Weight 848.81 g/mol Molecular Weight (Cu) N/A Amino Acids 9 Amino Acids Sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Stability Information
Protect from direct lightAvoid repeated freeze-thaw cyclesHigh stability in lyophilized form Lyophilized (powder) -20°C · up to 2 years Reconstituted 2-8°C · up to 30 days
About DSIP
DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring neuropeptide first isolated during slow-wave sleep studies. It serves as a subject of broader research into how the body manages sleep-wake cycles and neuroendocrine signaling.
Mechanism of Action
The mechanism of DSIP involves modulating the hypothalamic-pituitary-adrenal (HPA) axis. It influences the release of LH and cortisol while interacting with stress response pathways to stabilize circadian rhythms and manage oxidative stress in research models.
What Research Has Shown
Neuroendocrine Research 65 Sleep Cycle Improvement (%) Slow-Wave Sleep Induction DSIP Administered 65% Control Group 25% Trial details: Preclinical investigations exploring hypothalamic-pituitary signaling and cortisol release modulation in animal models. Research Findings
Circadian Rhythm Regulation
Observations from oxidative stress and nociception studies.
72% Cortisol Modulation Reduced Stress Response 68% Sleep Induction Enhanced Slow-Wave Activity Note: Results focus on neuroendocrine pathway interactions.
Research Highlights
Slow-Wave Sleep Induction
Exploration of DSIP’s ability to promote and sustain deep sleep phases in animal models.
Stress Pathway Modulation
Research focusing on the peptide’s interaction with cortisol and its role in oxidative stress regulation.
Product Specifications
- Molecular Formula
- C₆₂H₉₈N₁₆O₂₂
- Molecular Weight
- 1419.53 g/mol
- Sequence
- Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
- Purity
- ≥99% (HPLC verified)
- Form
- Lyophilized powder
- Appearance
- White to off-white powder
- Solubility
- Soluble in water, bacteriostatic water
- Storage
- -20°C (lyophilized), 2-8°C (reconstituted)
Research Studies
Neuropeptides in Sleep Signaling
A study on the isolation of DSIP and its direct effects on cerebral venous blood during sleep.
Monnier M. & Schoenenberger G.A. View Full Study Neuroendocrine Impact of DSIP
Analysis of hypothalamic-pituitary signaling and its influence on endocrine release.
Journal of Experimental Peptide Science (2019) View Full Study
Frequently Asked Questions
What is the primary focus of DSIP research?
Research primarily explores its role in slow-wave sleep, stress response pathways, and circadian rhythm modulation.
Is this product third-party tested?
Yes, every batch is tested via HPLC and mass spectrometry with a purity of ≥98%.
Frequently bought together: KissPeptin, GHK-Cu/KPV Blend, Ipamorelin
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