What Is Thymosin Alpha 1?
Type Immune Modulator CAS Number 62304-98-7 Molecular Weight 3108.3 g/mol Molecular Weight (Cu) N/A Amino Acids 28 Amino Acids Sequence Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH Formula C_{129}H_{215}N_{33}O_{55} Storage Requirements
Stability Information
High-purity lyophilized structureStable and consistent reagentAvoid repeated freeze-thaw cycles Lyophilized (powder) -20°C · up to 2 years Reconstituted 2-8°C · up to 30 days
About Thymosin Alpha 1
Thymosin Alpha-1 (Tα1) is a 28-amino acid synthetic peptide derived from thymic tissue. It serves as a vital tool for studying the immune system, particularly how the body regulates T-cell development and immune signaling pathways to maintain homeostasis.
Mechanism of Action
The mechanism involves Thymosin Alpha-1 modulating immune responses by influencing T-cell maturation and differentiation. It acts on signaling pathways that regulate cytokine production, thereby enhancing the host defense mechanisms and balancing innate and adaptive immunity in research settings.
What Research Has Shown
Immunology Research 98 Purity Percentage (HPLC) T-Cell Maturation Rate Tα1 Research Group 86.5% Control Group 38.0% Trial details: Investigative research focusing on immune signaling pathways and host defense mechanisms in experimental models. Immune Homeostasis
Immunomodulatory Mechanisms
Findings from cellular communication studies
86% T-Cell Differentiation Enhanced Adaptive Immune Signaling 78% Cytokine Regulation Optimized Inflammatory Response Note: Results focus on the peptide’s role in innate and adaptive immune signaling.
Research Highlights
T-Cell Development
Research focusing on the maturation and differentiation of T-cells induced by thymic peptides.
Cytokine Regulation
Investigating how Tα1 modulates the signaling pathways responsible for cytokine release.
Host Defense Mechanisms
Studies exploring the enhancement of adaptive immune responses against external stressors.
Peptide Stability Analysis
Exploration of the structural integrity and biochemical consistency of high-purity Tα1 in assays.
Product Specifications
- Molecular Formula
- C₆₂H₉₈N₁₆O₂₂
- Molecular Weight
- 1419.53 g/mol
- Sequence
- Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
- Purity
- ≥99% (HPLC verified)
- Form
- Lyophilized powder
- Appearance
- White to off-white powder
- Solubility
- Soluble in water, bacteriostatic water
- Storage
- -20°C (lyophilized), 2-8°C (reconstituted)
Research Studies
Thymic Peptides and Immune Signaling
A study on the role of Thymosin Alpha-1 in T-cell maturation and immune system modulation.
Goldstein A.L. & Badamchian M. View Full Study
Frequently Asked Questions
What is the origin of Thymosin Alpha-1?
It is a synthetic peptide originally derived from the naturally occurring thymic peptide thymosin fraction 5.
What are its primary research applications?
It is widely used to study T-cell maturation, cytokine regulation, and both innate and adaptive immune responses.
Frequently bought together: Sermorelin, Glutathione, Epithalon
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