AOD

What Is AOD?

Type hGH-derived Peptide Fragment CAS Number 221231-10-3 Molecular Weight 1815.08 g/mol Molecular Weight (Cu) N/A Amino Acids 16 Amino Acids (Tyr-hGH 177-191) Sequence Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe

Stability Information

High-purity synthetic peptide fragmentLyophilized powder (white/off-white)Protected from light and moisture Lyophilized (powder) –20 °C · up to 2 years Reconstituted 2-8°C · up to 30 days

About AOD

AOD-9604 is a synthetic peptide fragment derived from the C-terminal region of human growth hormone (hGH 177-191). This lyophilized peptide has been extensively studied in biochemical and metabolic research for its potential to influence lipolytic and anti-lipogenic pathways. By mimicking the region of hGH responsible for stimulating fat metabolism without affecting growth or insulin levels, AOD-9604 provides a valuable tool for in vitro and in vivo studies exploring energy balance, lipid mobilization, and peptide signaling. It is intended strictly for laboratory and research purposes only.

Mechanism of Action

The mechanism involves AOD-9604 binding to specific receptors on adipocytes (fat cells), mimicking the lipolytic effect of the full human growth hormone. It triggers the breakdown of fats (lipolysis) and inhibits the transformation of non-fatty foods into body fat (lipogenesis). Unlike full-length hGH, it targets fat metabolism specifically, avoiding the systemic increase in insulin-like growth factor (IGF-1) and minimizing effects on blood glucose levels in experimental research assays.

What Research Has Shown

Metabolic Research 98 Purity Percentage (HPLC verified) Lipid Mobilization & Lipolysis AOD-9604 Treated 86.5% Control Group 14.0% Trial details: Investigative studies focusing on the mechanistic research of energy regulation and adipocyte function in preclinical pharmacological assays Bioenergetic Results

Energy Balance & Lipid Turnover

Findings from fat metabolism and hGH-derived fragment studies

89% Lipolysis Stimulated Fat Metabolism 82% Anti-lipogenic Inhibited Lipid Formation Note: Results highlight the compound’s value in exploring molecular pathways for energy regulation.

Research Highlights

Fat Metabolism Mechanisms

Mechanistic research on how hGH-derived fragments influence energy regulation.

Adipocyte Function Studies

Investigating lipid turnover and mobilization within adipose tissue models.

Energy Balance Research

Studies exploring the physiological regulation of energy intake and expenditure using peptide fragments.

Analytical Assay Development

Use as a high-purity reference standard in pharmacological and preclinical peptide behavior profiling.

Product Specifications

• Molecular Formula
• C₆₂H₉₈N₁₆O₂₂
• Molecular Weight
• 1419.53 g/mol
• Sequence
• Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
• Purity
• ≥99% (HPLC verified)
• Form
• Lyophilized powder
• Appearance
• White to off-white powder
• Solubility
• Soluble in water, bacteriostatic water
• Storage
• -20°C (lyophilized), 2-8°C (reconstituted)

Research Studies

AOD-9604: A C-Terminal Fragment for Metabolic Research

A comprehensive analysis of the lipolytic and anti-lipogenic pathways in hGH-derived fragments.

Heffernan M.A. & Ng F.M. View Full Study

Frequently Asked Questions

What is the specific origin of AOD-9604?

It is a synthetic peptide fragment derived from the C-terminal region of human growth hormone, specifically residues 177-191.

Does AOD-9604 affect growth or insulin levels?

Research indicates that it mimics the fat-metabolizing region of hGH without impacting overall growth or blood insulin levels in laboratory models.

Frequently bought together: MOTS-C, Lipo-C (B6 & B12 added), Cagri