DSIP

What Is DSIP?

Type Sleep Modulator CAS Number 62568-57-4 Molecular Weight 848.81 g/mol Molecular Weight (Cu) N/A Amino Acids 9 Amino Acids Sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu

Stability Information

Protect from direct lightAvoid repeated freeze-thaw cyclesHigh stability in lyophilized form Lyophilized (powder) -20°C · up to 2 years Reconstituted 2-8°C · up to 30 days

About DSIP

DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring neuropeptide first isolated during slow-wave sleep studies. It serves as a subject of broader research into how the body manages sleep-wake cycles and neuroendocrine signaling.

Mechanism of Action

The mechanism of DSIP involves modulating the hypothalamic-pituitary-adrenal (HPA) axis. It influences the release of LH and cortisol while interacting with stress response pathways to stabilize circadian rhythms and manage oxidative stress in research models.

What Research Has Shown

Neuroendocrine Research 65 Sleep Cycle Improvement (%) Slow-Wave Sleep Induction DSIP Administered 65% Control Group 25% Trial details: Preclinical investigations exploring hypothalamic-pituitary signaling and cortisol release modulation in animal models. Research Findings

Circadian Rhythm Regulation

Observations from oxidative stress and nociception studies.

72% Cortisol Modulation Reduced Stress Response 68% Sleep Induction Enhanced Slow-Wave Activity Note: Results focus on neuroendocrine pathway interactions.

Research Highlights

Slow-Wave Sleep Induction

Exploration of DSIP’s ability to promote and sustain deep sleep phases in animal models.

Stress Pathway Modulation

Research focusing on the peptide’s interaction with cortisol and its role in oxidative stress regulation.

Product Specifications

• Molecular Formula
• C₆₂H₉₈N₁₆O₂₂
• Molecular Weight
• 1419.53 g/mol
• Sequence
• Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
• Purity
• ≥99% (HPLC verified)
• Form
• Lyophilized powder
• Appearance
• White to off-white powder
• Solubility
• Soluble in water, bacteriostatic water
• Storage
• -20°C (lyophilized), 2-8°C (reconstituted)

Research Studies

Neuropeptides in Sleep Signaling

A study on the isolation of DSIP and its direct effects on cerebral venous blood during sleep.

Monnier M. & Schoenenberger G.A. View Full Study Neuroendocrine Impact of DSIP

Analysis of hypothalamic-pituitary signaling and its influence on endocrine release.

Journal of Experimental Peptide Science (2019) View Full Study

Frequently Asked Questions

What is the primary focus of DSIP research?

Research primarily explores its role in slow-wave sleep, stress response pathways, and circadian rhythm modulation.

Is this product third-party tested?

Yes, every batch is tested via HPLC and mass spectrometry with a purity of ≥98%.

Frequently bought together: KissPeptin, GHK-Cu/KPV Blend, Ipamorelin